Effect of wearing a face mask on fMRI BOLD contrast.
Identifieur interne : 000077 ( Main/Exploration ); précédent : 000076; suivant : 000078Effect of wearing a face mask on fMRI BOLD contrast.
Auteurs : Christine S W. Law [États-Unis] ; Patricia S. Lan [États-Unis] ; Gary H. Glover [États-Unis]Source :
- NeuroImage [ 1095-9572 ] ; 2021.
Abstract
International spread of the coronavirus SARS-CoV-2 has prompted many MRI scanning facilities to require scan subjects to wear a facial covering ("mask") during scanning as a precaution against transmission of the virus. Because wearing a mask mixes expired air with the subject's inspired air stream, the concentration of inspired carbon dioxide [CO2] is elevated, resulting in mild hypercapnia. Changes in the inspired gas mixture have been demonstrated to alter R2*-weighted Blood Oxygen Dependent (BOLD) contrast. In this study, we investigate a potential for face masking to alter BOLD contrast during a sensory-motor task designed to activate visual, auditory, and sensorimotor cortices in 8 subjects. We utilize a nasal cannula to supply air to the subject wearing a surgical mask in on-off blocks of 90s to displace expired CO2, while the subject performs the sensory-motor task. While only a small fraction (2.5%) of the sensory-motor task activation is related to nasal air modulation, a 30.0% change in gray matter BOLD signal baseline is found due to air modulation. Repeating the scan with mask removed produces a small subject-specific bias in BOLD baseline signal from nasal air supply, which may be due to cognitive influence of airflow or cannula-induced hypoxia. Measurements with capnography demonstrate wearing a mask induces an average increase in ETCO2 of 7.4%. Altogether, these results demonstrate that wearing a face mask during gradient-echo fMRI can alter BOLD baseline signal but minimally affects task activation.
DOI: 10.1016/j.neuroimage.2021.117752
PubMed: 33460795
PubMed Central: PMC7809431
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of wearing a face mask on fMRI BOLD contrast.</title><author><name sortKey="Law, Christine S W" sort="Law, Christine S W" uniqKey="Law C" first="Christine S W" last="Law">Christine S W. Law</name><affiliation wicri:level="1"><nlm:affiliation>Systems Neuroscience and Pain Lab, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, 94304, USA. Electronic address: cslaw@stanford.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Systems Neuroscience and Pain Lab, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, 94304</wicri:regionArea><wicri:noRegion>94304</wicri:noRegion></affiliation></author><author><name sortKey="Lan, Patricia S" sort="Lan, Patricia S" uniqKey="Lan P" first="Patricia S" last="Lan">Patricia S. Lan</name><affiliation wicri:level="4"><nlm:affiliation>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305</wicri:regionArea><orgName type="university">Université Stanford</orgName><placeName><settlement type="city">Stanford (Californie)</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Glover, Gary H" sort="Glover, Gary H" uniqKey="Glover G" first="Gary H" last="Glover">Gary H. Glover</name><affiliation wicri:level="4"><nlm:affiliation>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305</wicri:regionArea><orgName type="university">Université Stanford</orgName><placeName><settlement type="city">Stanford (Californie)</settlement><region type="state">Californie</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021</date><idno type="RBID">pubmed:33460795</idno><idno type="pmid">33460795</idno><idno type="doi">10.1016/j.neuroimage.2021.117752</idno><idno type="pmc">PMC7809431</idno><idno type="wicri:Area/Main/Corpus">000032</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000032</idno><idno type="wicri:Area/Main/Curation">000032</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000032</idno><idno type="wicri:Area/Main/Exploration">000032</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of wearing a face mask on fMRI BOLD contrast.</title><author><name sortKey="Law, Christine S W" sort="Law, Christine S W" uniqKey="Law C" first="Christine S W" last="Law">Christine S W. Law</name><affiliation wicri:level="1"><nlm:affiliation>Systems Neuroscience and Pain Lab, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, 94304, USA. Electronic address: cslaw@stanford.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Systems Neuroscience and Pain Lab, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, 94304</wicri:regionArea><wicri:noRegion>94304</wicri:noRegion></affiliation></author><author><name sortKey="Lan, Patricia S" sort="Lan, Patricia S" uniqKey="Lan P" first="Patricia S" last="Lan">Patricia S. Lan</name><affiliation wicri:level="4"><nlm:affiliation>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305</wicri:regionArea><orgName type="university">Université Stanford</orgName><placeName><settlement type="city">Stanford (Californie)</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Glover, Gary H" sort="Glover, Gary H" uniqKey="Glover G" first="Gary H" last="Glover">Gary H. Glover</name><affiliation wicri:level="4"><nlm:affiliation>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305</wicri:regionArea><orgName type="university">Université Stanford</orgName><placeName><settlement type="city">Stanford (Californie)</settlement><region type="state">Californie</region></placeName></affiliation></author></analytic><series><title level="j">NeuroImage</title><idno type="eISSN">1095-9572</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">International spread of the coronavirus SARS-CoV-2 has prompted many MRI scanning facilities to require scan subjects to wear a facial covering ("mask") during scanning as a precaution against transmission of the virus. Because wearing a mask mixes expired air with the subject's inspired air stream, the concentration of inspired carbon dioxide [CO<sub>2</sub>] is elevated, resulting in mild hypercapnia. Changes in the inspired gas mixture have been demonstrated to alter R2*-weighted Blood Oxygen Dependent (BOLD) contrast. In this study, we investigate a potential for face masking to alter BOLD contrast during a sensory-motor task designed to activate visual, auditory, and sensorimotor cortices in 8 subjects. We utilize a nasal cannula to supply air to the subject wearing a surgical mask in on-off blocks of 90s to displace expired CO<sub>2</sub>, while the subject performs the sensory-motor task. While only a small fraction (2.5%) of the sensory-motor task activation is related to nasal air modulation, a 30.0% change in gray matter BOLD signal baseline is found due to air modulation. Repeating the scan with mask removed produces a small subject-specific bias in BOLD baseline signal from nasal air supply, which may be due to cognitive influence of airflow or cannula-induced hypoxia. Measurements with capnography demonstrate wearing a mask induces an average increase in ETCO<sub>2</sub> of 7.4%. Altogether, these results demonstrate that wearing a face mask during gradient-echo fMRI can alter BOLD baseline signal but minimally affects task activation.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33460795</PMID><DateRevised><Year>2021</Year><Month>01</Month><Day>29</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1095-9572</ISSN><JournalIssue CitedMedium="Internet"><Volume>229</Volume><PubDate><Year>2021</Year><Month>Jan</Month><Day>15</Day></PubDate></JournalIssue><Title>NeuroImage</Title><ISOAbbreviation>Neuroimage</ISOAbbreviation></Journal><ArticleTitle>Effect of wearing a face mask on fMRI BOLD contrast.</ArticleTitle><Pagination><MedlinePgn>117752</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1053-8119(21)00029-X</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.neuroimage.2021.117752</ELocationID><Abstract><AbstractText>International spread of the coronavirus SARS-CoV-2 has prompted many MRI scanning facilities to require scan subjects to wear a facial covering ("mask") during scanning as a precaution against transmission of the virus. Because wearing a mask mixes expired air with the subject's inspired air stream, the concentration of inspired carbon dioxide [CO<sub>2</sub>] is elevated, resulting in mild hypercapnia. Changes in the inspired gas mixture have been demonstrated to alter R2*-weighted Blood Oxygen Dependent (BOLD) contrast. In this study, we investigate a potential for face masking to alter BOLD contrast during a sensory-motor task designed to activate visual, auditory, and sensorimotor cortices in 8 subjects. We utilize a nasal cannula to supply air to the subject wearing a surgical mask in on-off blocks of 90s to displace expired CO<sub>2</sub>, while the subject performs the sensory-motor task. While only a small fraction (2.5%) of the sensory-motor task activation is related to nasal air modulation, a 30.0% change in gray matter BOLD signal baseline is found due to air modulation. Repeating the scan with mask removed produces a small subject-specific bias in BOLD baseline signal from nasal air supply, which may be due to cognitive influence of airflow or cannula-induced hypoxia. Measurements with capnography demonstrate wearing a mask induces an average increase in ETCO<sub>2</sub> of 7.4%. Altogether, these results demonstrate that wearing a face mask during gradient-echo fMRI can alter BOLD baseline signal but minimally affects task activation.</AbstractText><CopyrightInformation>Copyright © 2021. Published by Elsevier Inc.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Law</LastName><ForeName>Christine S W</ForeName><Initials>CSW</Initials><AffiliationInfo><Affiliation>Systems Neuroscience and Pain Lab, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, 94304, USA. Electronic address: cslaw@stanford.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lan</LastName><ForeName>Patricia S</ForeName><Initials>PS</Initials><AffiliationInfo><Affiliation>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Glover</LastName><ForeName>Gary H</ForeName><Initials>GH</Initials><AffiliationInfo><Affiliation>Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, CA, 94305, USA; Department of Radiology, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2021</Year><Month>01</Month><Day>15</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Neuroimage</MedlineTA><NlmUniqueID>9215515</NlmUniqueID><ISSNLinking>1053-8119</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">BOLD contrast</Keyword><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Facial covering</Keyword><Keyword MajorTopicYN="N">Mask</Keyword><Keyword MajorTopicYN="N">SARS-CoV2</Keyword><Keyword MajorTopicYN="N">fMRI</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest The authors declare no conflict of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>10</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>12</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2021</Year><Month>01</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>1</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>1</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>1</Month><Day>18</Day><Hour>20</Hour><Minute>10</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33460795</ArticleId><ArticleId IdType="pii">S1053-8119(21)00029-X</ArticleId><ArticleId IdType="doi">10.1016/j.neuroimage.2021.117752</ArticleId><ArticleId IdType="pmc">PMC7809431</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region><settlement><li>Stanford (Californie)</li></settlement><orgName><li>Université Stanford</li></orgName></list><tree><country name="États-Unis"><noRegion><name sortKey="Law, Christine S W" sort="Law, Christine S W" uniqKey="Law C" first="Christine S W" last="Law">Christine S W. Law</name></noRegion><name sortKey="Glover, Gary H" sort="Glover, Gary H" uniqKey="Glover G" first="Gary H" last="Glover">Gary H. Glover</name><name sortKey="Lan, Patricia S" sort="Lan, Patricia S" uniqKey="Lan P" first="Patricia S" last="Lan">Patricia S. Lan</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidStanfordV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000077 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000077 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidStanfordV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:33460795
|texte= Effect of wearing a face mask on fMRI BOLD contrast.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:33460795" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidStanfordV1
| This area was generated with Dilib version V0.6.38. |  |